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PREVENTION OF AND THERAPY FOR RADIATION TOXICITY OF NORMAL TISSUES USING DRUGS WHICH BLOCK IL-1 ACTIVITY
PREVENTION OF AND THERAPY FOR RADIATION TOXICITY OF NORMAL TISSUES USING DRUGS WHICH BLOCK IL-1 ACTIVITY
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机译:IL-1活性药物对正常组织辐射毒性的预防和治疗
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摘要
A method for the prevention of and therapy for radiation pneumonitis, dermatitis, soft tissue fibrosis and central nervous system toxicity in patients undergoing therapeutic radiation. In addition, the invention provides for pre-treatment of those responding to nuclear bio terrorism or other nuclear or radiological accidents. Thus, with the present invention, subjects may be treated in order to prevent toxicity from nuclear bio terrorism or other nuclear or radiological accidents. More particularly, we have discovered a method for prophylactically treating radiation toxicity in normal tissue of subject comprising administering an anti-radiation toxicity effective amount of a cytokine blocking agent through the subject. More specifically, we have discovered a method for prophylactically treating radiation pneumonitis, dermatitis, soft tissue fibrosis or central nervous system toxicity in a subject comprising administering an anti-radiation pneumonitis, dermatitis, soft tissue fibrosis or central nervous system toxicity effective amount of a cytokine blocking agent to the subject.
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