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Quercitrin for preventing and curing diabetic symptoms manufacturing method thereof and ethanol extract of the bark of Illicium religiosum for preventing and curing diabetic symptoms comprising quercitrin
Quercitrin for preventing and curing diabetic symptoms manufacturing method thereof and ethanol extract of the bark of Illicium religiosum for preventing and curing diabetic symptoms comprising quercitrin
PURPOSE: A composition containing quercitrin separated from an ethanol extract of the bark of Illicium religiosum Sieb. et Zucc. is provided which has an excellent aldose reductase inhibiting effect, markedly inhibits accumulation of sorbitol and is effective in prevention and treatment of diabetic causing complications such as retinopathy, nephropathy, neuropathy or the like. CONSTITUTION: Quercitrin for prophylaxis and treatment of diabetic is quercitrin-3-o--L-rhamnoside. The bark of Illicium religiosum Sieb. et Zucc. is dried, ground, mixed 10 to 30 times(w/v) with ethanol and extracted at room temperature continuously 2 to 5 times. The extract is filtered with a filter paper of 5 to 10m, concentrated at 0 to 60deg.C under vacuum, fractionated by adding 10 to 30 times with distilled water and ethyl acetate and then concentrated.
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机译:用途:一种组合物,其包含从槲皮白皮树皮的乙醇提取物中分离的槲皮素。 et Zucc。本发明提供了具有优异的醛糖还原酶抑制作用,显着抑制山梨糖醇蓄积并有效预防和治疗由糖尿病引起的诸如视网膜病,肾病,神经病等并发症的方法。组成:槲皮素用于糖尿病的预防和治疗是槲皮素-3-邻-L-鼠李糖苷。 Illicium religiosum Sieb的树皮。 et Zucc。将其干燥,研磨,与乙醇混合10至30倍(w / v),并在室温下连续提取2至5次。萃取物用5至10m的滤纸过滤,在0至60℃在真空下浓缩,通过用蒸馏水和乙酸乙酯添加10至30次而分馏,然后浓缩。
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