SENESCENCE MARKER PROTEIN 30-DEFICIENT ANIMAL, ANTIBODY AND METHOD FOR PREPARING THE ANTIBODY

摘要

PPROBLEM TO BE SOLVED: To provide a nonhuman animal deficient in SMP30 (senescence marker protein 30) gene, an antibody using the animal and a method for preparing the same, or the like. PSOLUTION: A mutant type SMP30 gene deficient in functions is prepared as follows. At least a part of a DNA sequence of a chromosomal SMP30 gene is made deficient or substituted with another sequence. Otherwise, the other sequence is inserted into the gene. PCOPYRIGHT: (C)2004,JPO&NCIPI