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Compounds affecting CD83 expression, pharmaceutical compositions containing said compounds and methods for identifying said compounds

机译:影响CD83表达的化合物,包含所述化合物的药物组合物和鉴定所述化合物的方法

摘要

The present invention relates to compounds that specifically block the binding between a member of the HuR family of proteins and a mRNA encoding a member of the CD83 family of proteins and that reduce expression of a member of the CD83 family of proteins in a cell as well as pharmaceutical compositions comprising such compounds and methods for screening and/or identifying compounds that block the binding between a member of the HuR family of proteins and a mRNA encoding a member of the CD83 family of proteins.
机译:本发明涉及特异性阻断HuR蛋白家族成员与编码CD83蛋白家族成员的mRNA之间的结合并且还降低细胞中CD83蛋白家族成员的表达的化合物。包含此类化合物的药物组合物以及用于筛选和/或鉴定阻断HuR蛋白家族成员与编码CD83蛋白家族成员的mRNA之间结合的化合物的方法。

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