ENCEPHALOPATHY THERAPEUTIC AGENT AND METHOD OF TREATING ENCEPHALOPATHY

摘要

PROBLEM TO BE SOLVED: To provide an encephalopathy therapeutic agent ameliorating encephalopathy due to an alkylphenolic compound, to provide a method for treating the encephalopathy, and to provide a cerebral function-ameliorating drug having the efficacy such as the effect of inhibiting/ameliorating tubulin polymerization. ;SOLUTION: The encephalopathy therapeutic agent comprises a steroid (preferably, neuro-steroid, especially pregnenolone) which ameliorates the encephalopathy due to the alkylphenolic compound; wherein, more specifically, said encephalopathy is caused by acting on MAP2 (microtubule-associated protein 2), and said alkylphenolic compound is nonylphenol.;COPYRIGHT: (C)2004,JPO