Detecting binding of mrna to an oligonucleotide array using rna dependent nucleic acid modifying enzymes

摘要

This invention relates to both a device and a method for detecting and binding of mRNA to oligonucleotides on an array. The oligonucleotides on the array have a reactive-OH group at their free 3′ end, and the binding of mRNA is detected using RNA dependent nucleic acid modifying enzymes.