Detection of the binding of mRNA to oligonucleotide arrays using RNA-dependent nucleic acid modifying enzymes

摘要

This invention relates to both a device and a method for detecting and binding of mRNA to oligonucleotides on an array. The oligonucleotides on the array have a reactive-OH group at their free 3' end, and the binding of mRNA is detected using RNA dependent nucleic acid modifying enzymes.