Method for identifying a disease state based on a detected mixture of activated transcription factors

摘要

Methods, arrays and kits are provided for rapidly and efficiently identifying the cell type of a cell sample. In one embodiment, the method includes the step of mixing a library of double-stranded DNA probes with a cell sample containing activated transcription factors. The DNA probes that have bound to the activated transcription factors may be isolated from the complexes formed between the probes and the activated transcription factors. The bound probes can be identified, for example, by using an array of hybridization probes, which leads to the determination of the cell type of the cell sample based on the correlation between the identified DNA probes and their corresponding transcription factors.