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Bacterial carboxypeptidase cpg2 variants and their use in gene directed enzyme prodrug therapy

机译:细菌羧肽酶cpg2变体及其在基因定向酶前药治疗中的应用

摘要

The present invention relates to bacterial carboxypeptidases for use in gene directed prodrug therapy, in particular for use in the treatment of disease, including tumors. Specifically, the invention relates to modified bacterial carboxypeptidases which have enhanced catalytic activity.
机译:本发明涉及用于基因定向前药治疗的细菌羧肽酶,特别是用于治疗包括肿瘤在内的疾病。具体地,本发明涉及具有增强的催化活性的修饰的细菌羧肽酶。

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