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Recombinant immunogenic compositions and methods for protecting against lethal infections from Bacillus anthracis
Recombinant immunogenic compositions and methods for protecting against lethal infections from Bacillus anthracis
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机译:重组免疫原性组合物和防止炭疽芽孢杆菌致死性感染的方法
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摘要
Recombinant immunogenic compositions and methods for protecting against lethal infections from Bacillus anthracis having a variant of recombinant Bacillus anthracis protective antigen (rPA) and a variant of recombinant Bacillus anthracis lethal factor (rLF). These proteins may be expressed separately or as a fusion protein. The recombinant proteins are produced in an avirulent strain of Bacillus anthracis that overproduces the desired antigens. The compositions and methods induce the animal host to produce antibodies against a virulent strain of Bacillus anthracis. 展开▼