A therapeutic agent for treating diseases caused by retroviruses is provided. The agent acts by inducing secretion of biological anti-microbial peptides. Specifically, the therapeutic agent is intended to treat retroviral infections and contains as an active ingredient fermentation products produced by yeasts and lactic acid bacteria. Among the diseases caused by retrovirus that can be treated with the therapeutic agent are acquired immune deficiency syndrome (AIDS) and adult T-cell leukemia (ATL) caused by human T-cell lymphotropic virus-I (HTLV-I).
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