首页> 外国专利> Use of compounds that are combinations of selective antagonists of dopamine D2 Receptor Antagonists and agonists Selective 5-ht2a receptor, and Pharmaceutical Preparations Containing these compounds

Use of compounds that are combinations of selective antagonists of dopamine D2 Receptor Antagonists and agonists Selective 5-ht2a receptor, and Pharmaceutical Preparations Containing these compounds

机译:多巴胺D2受体拮抗剂和选择性5-ht2a受体激动剂的选择性拮抗剂组合的化合物的用途以及含有这些化合物的药物制剂

摘要

Use of combinations of compounds which are Selective antagonists of dopamine D2 receptor and 5-ht1a receptor agonists, in particular (R) - (-) - 2 - [5 - (4-fluorophenyl) - 3 - piridilmetilaminometil chromane] - or Salt acceptable to use the same Physiological or N - (4 3 '- fluoro - bifenilmetil) - N - [2 - (3 - C Iano phenoxy ethyl) Amine or a Salt of the same Physiological acceptable for use.In the preparation of a Medicine for Veterinary medicine for the Treatment or prophylaxis of disorders associated with traumatic stressors self-directed behavior, compulsive Disorders associated with stressors and / or Behavioral Disorders anxiety Stressors associated with the behavior.Pharmaceutical preparation for use in Veterinary medicine for the treatment of disorders associated with Behavioral stressors that contains a combination of at least a dopamine D2 receptor antagonist and agonist of the 5-ht1a receptor.In particular, (R) - (-) - 2 - [5 - (4 - fluoro phenyl) - 3 - piridilmetilaminometil chromane] - or Salt acceptable to use the same Physiological or N - (4 '- fluoro - 3 - bifenilmetil) - N - [2 - (3 - cyano - phenoxy Ethyl amine Salt) or A physiologically acceptable for use in the same.
机译:作为多巴胺D2受体和5-ht1a受体激动剂的选择性拮抗剂的化合物的组合的用途,尤其是(R)-(-)-2-[5-(4-氟苯基)-3-piridilmetilaminometil chromane]-或盐可接受使用相同的生理学或N-(4 3'-氟-联苯甲胺基)-N-[2--(3-C碘代苯氧基乙基)胺或相同生理学上可接受的盐。用于治疗或预防与创伤性应激源有关的自我指导行为,与应激源相关的强迫性疾病和/或行为紊乱焦虑相关的疾病的兽医。与该行为相关的兽医制剂行为压力源,包含至少多巴胺D2受体拮抗剂和5-ht1a受体激动剂的组合。尤其是(R)-(-)-2-[5-(4-氟苯基)-3-哌啶酮基氨基甲基苯丙氨酸]-或使用相同生理学可接受的盐或N-(4'-氟-3-联苯甲腈)-N-[2-(3--氰基-苯氧基乙胺盐)或生理学可接受用于同一生理盐水。

著录项

  • 公开/公告号AR035503A1

    专利类型

  • 公开/公告日2004-06-02

    原文格式PDF

  • 申请/专利号AR2001P105302

  • 发明设计人 BARTOSZYK GERD;

    申请日2001-11-14

  • 分类号A61K31/00;A61K31/4433;A61K31/275;A61P25/22;A61P25/18;A61P43/00;

  • 国家 AR

  • 入库时间 2022-08-21 23:12:23

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