首页> 外国专利> Preparation comprising a plurality of factor vii polypeptides, methods for determining the pattern of factor vii glycoform and factor vii-related polypeptides, and for producing said preparation, pharmaceutical formulation, methods for treating a factor responsive syndrome. vii, for the prevention of unwanted bleeding, for the prevention of unwanted blood clotting, and for the prevention of tissue factor mediated reactions, and the use of the preparation.

Preparation comprising a plurality of factor vii polypeptides, methods for determining the pattern of factor vii glycoform and factor vii-related polypeptides, and for producing said preparation, pharmaceutical formulation, methods for treating a factor responsive syndrome. vii, for the prevention of unwanted bleeding, for the prevention of unwanted blood clotting, and for the prevention of tissue factor mediated reactions, and the use of the preparation.

机译:包含多种因子VII多肽的制剂,用于确定因子VII糖型和因子VII相关多肽的模式的方法,以及用于产生所述制剂的药物制剂,用于治疗因子反应综合征的方法。 vii,用于防止不想要的出血,用于防止不想要的血液凝结,以及用于防止组织因子介导的反应,以及该制剂的用途。

摘要

"PREPARATION UNDERSTANDING A PLURALITY OF Factor VII polypeptides, methods for the determination of Factor VII glycoform standard and polypeptides related to Factor VII, and for the production of DITA PREPARATION A MATERIALS Factor VII for the prevention of unwanted bleeding, for the prevention of unwanted blood coagulation, and for the prevention of tissue-mediated reactions and the use of preparation ". The present invention relates to compositions comprising Factor VII and other blood coagulation factors having altered asparagine-linked glycosylation patterns.
机译:“认识到多种因子VII多肽的制备方法,确定因子VII糖型标准品和与因子VII有关的多肽以及制备DITA的材料制备因子VII用于预防不想要的出血,预防不想要的血液凝结,并用于预防组织介导的反应和制剂的使用”。本发明涉及包含因子VII和其他具有改变的天冬酰胺连接的糖基化模式的凝血因子的组合物。

著录项

  • 公开/公告号BR0114374A

    专利类型

  • 公开/公告日2003-12-30

    原文格式PDF

  • 申请/专利权人 NOVO NORDISK A/S;

    申请/专利号BR20010114374

  • 发明设计人 HANS KURT PINGEL;NIELS KRISTIAN KLAUSEN;

    申请日2001-10-02

  • 分类号C12N9/64;A61K38/36;C12P21/02;G01N33/86;

  • 国家 BR

  • 入库时间 2022-08-21 23:12:15

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