Process for producing mature in vitro dendritic cells, method for producing a vaccine to induce a cellular immune response in a human or animal body, vaccine and specifically configured high molecular weight double stranded polymer

摘要

"PROCESS FOR PRODUCING MATURE DENTRIC CELLS IN VITRO, METHOD FOR PRODUCING A VACCINE FOR INDUCING A CELL IMMUNE RESPONSE IN A HUMAN OR ANIMAL BODY, VACCINE AND POLYMER DOUBLE TAPE RNA WITH A SPECIFICALLY SPECIFICALLY DIFFICULATED WEIGHT. The invention provides a method for producing mature in vitro dendritic cells, which comprises the step of culturing immature dendritic cells in the presence of a specifically configured high molecular weight double stranded RNA (dsRNA) polymer. The specifically configured high molecular weight dsRNA polymer is typically selected from the group comprising poly [I]: poly [CxU]; poly [I]: poly [GxU]; poly [A]: poly [UxC]; poly [A]: poly [UxG] poly [U]: poly [AxC]: poly [U]: poly [IxU]; poly [C]: poly [GxA]; poly [C]: poly [GxU]; poly [G] -pollu [CXA]; poly [G]: poly [CxU] and Ampligen, where x is a proportion of a number from 3 to 40. Immature dendritic cells can be exposed to an antigen before it is matured, and a vaccine including mature dendritic cells showing Antigen can then be prepared. A method for treating cancer, a virus, a parasite and a microorganism is also described.