'N3 benzimidazole derivatives as inhibitors of MEK' rented 'benzimimidazole N3 alkylated derivatives as MEK inhibitors

摘要

Table 1 lists the pharmaceutically acceptable formula I compounds and salts and their derivatives, where W, R1, R2, R7, R8, R9 and R10 are defined in the explanatory report. These compounds are MEK inhibitors and useful tools for the treatment of highly proliferative diseases such as breast cancer and inflammation. It also revealed a method of using this compound in the treatment of highly proliferative diseases by maqmiferos, as well as the synthesis of drugs containing this compound.