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N3 alkylated benzimidazole derivatives as inhibitors of MEK (N3 alkylated benzimidazole

机译:N3烷基化的苯并咪唑衍生物作为MEK抑制剂(N3烷基化的苯并咪唑

摘要

Disclosed are compounds of the formula and pharmaceutically acceptable Salts and prodrugs thereof, wherein W, T, R11 and R12 are as defined in the specification. These compounds are inhibitors of MEK and are useful in the treatment of hyperproliferative diseases, such as Cancer and inflammation, in Mammals.It also reveals a method for using these compounds for the treatment of hyperproliferative diseases and Pharmaceutical compositions containing such compounds.
机译:公开了下式的化合物及其药学上可接受的盐和前药,其中W,T,R 11和R 12如说明书中所定义。这些化合物是MEK的抑制剂,可用于治疗哺乳动物的过度增生性疾病,例如癌症和炎症。它还揭示了使用这些化合物治疗过度增生性疾病的方法以及含有此类化合物的药物组合物。

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