首页> 外国专利> Macrocyclic NS3-serine protease inhibitors of hepatitis C virus comprising alkyl and aryl alanine P2 moieties.

Macrocyclic NS3-serine protease inhibitors of hepatitis C virus comprising alkyl and aryl alanine P2 moieties.

机译:丙型肝炎病毒的大环NS3-丝氨酸蛋白酶抑制剂,包括烷基和芳基丙氨酸P2部分。

摘要

The present invention discloses novel macrocyclic compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such macrocycles as well as methods of using them to treat disorders associated with the HCV protease.
机译:本发明公开了具有HCV蛋白酶抑制活性的新型大环化合物及其制备方法。在另一个实施方案中,本发明公开了包含此类大环化合物的药物组合物,以及使用它们治疗与HCV蛋白酶相关的疾病的方法。

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