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METHODS AND PHARMACEUTICAL COMPOSITIONS FOR GROWTH PREVENTION OF TUMOR CELLS CONTAINING A PPAR-GAMMA AGONIST AND A MAP KINASE INHIBITOR
METHODS AND PHARMACEUTICAL COMPOSITIONS FOR GROWTH PREVENTION OF TUMOR CELLS CONTAINING A PPAR-GAMMA AGONIST AND A MAP KINASE INHIBITOR
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机译:预防含有PPAR-γ激动剂和MAP激酶抑制剂的肿瘤细胞生长的方法和药物成分
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摘要
Method of treating or inhibiting proliferation of a peroxisome proliferator-activated receptor (PPAR) gamma -responsive cell, comprising contacting the cell with a PPARgamma agonist. Also claimed is a composition comprising: (a) a PPARgamma ligand to induce terminal differentiation of a PPARgamma -responsive hyperproliferative cells in animals; (b) at least one agent selected from mitotic inhibitors, alkylating agents, antimetabolites, nucleic acid intercalating agents, topoisomerase inhibitors, agents which promote apoptosis and agents which increase immune responses to tumours; and (c) a carrier.
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