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methods and pharmaceutical compositions for wachstumsverhinderung of tumor cells containing a ppar gamma agonist and a map kinase inhibitor
methods and pharmaceutical compositions for wachstumsverhinderung of tumor cells containing a ppar gamma agonist and a map kinase inhibitor
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机译:pparγ激动剂和图激酶抑制剂的肿瘤细胞的方法和药物组合物
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摘要
Method of treating or inhibiting proliferation of a peroxisome proliferator-activated receptor (PPAR) gamma -responsive cell, comprising contacting the cell with a PPARgamma agonist. Also claimed is a composition comprising: (a) a PPARgamma ligand to induce terminal differentiation of a PPARgamma -responsive hyperproliferative cells in animals; (b) at least one agent selected from mitotic inhibitors, alkylating agents, antimetabolites, nucleic acid intercalating agents, topoisomerase inhibitors, agents which promote apoptosis and agents which increase immune responses to tumours; and (c) a carrier.
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