PROCEDURES TO INDUIT THE PRODUCTION OF ANTIBODIES AGAINST THE BACTERIA OF THE FAMILY CS4-CFA / 1 OF E. COLI.

摘要

A PEPTIDE CONSENSUS OF 36 AMINO ACIDS HAS BEEN DESIGNED TO ACT AS AN IMMUNOGEN FOR THE OBTAINING OF ANTIBODIES AGAINST THE PROTEINS OF ALL THE FAMILY MEMBERS OF E. COLI CS4 DENTIDAD, THE REST OF THE SEQUENCE OF THE PROTEINS SHOWS THEM A LOT. Strains THE PROTEIN REGION REPRESENTED IN THE SUBUNITY INCLUDES LINEAR KNOWN EPITOPES OF B AND T CELLS OF CFA / 1. THE CONSENSUS PEPTIDE HAS AN ELEVATED DEGREE OF HOMOLOGY WITH BEARING VINETS OF SIX DIFFERENT COLONIZATION FACTORS. THE CONSENSUS PEPTIDE HAS THE FORMULA: ** FORMULA **. AN ALTERNATIVE PEPTIDE, IDENTIFIED AS THE CONSENSUS PEPTIDE 2 HAS THE FORMULA: ** FORMULA **.