USE OF PIPERAZINE DERIVATIVES AS CCR1 ANTAGONISTS

摘要

The present invention relates to compounds of the formula (I) and thepharmaceutically acceptable forms thereof; wherein X, Y, a, b, c, d, R1, R2,R3, R4 and R5 are as defined herein. Moreover, the present invention is alsodirected at pharmaceutical compositions comprising a compound of the formula(I) and a pharmaceutically acceptable carrier. Furthermore, the presentinvention is directed at methods of using the herein described compounds andcompositions for treating or preventing a disorder or condition that can betreated or prevented by antagonizing the CCR1 receptor in a mammal.