MODULATORS OF TNF-ALPHA AND IL-1 CELL SURFACE RECEPTOR ACTIVITY

摘要

Methods and reagents for modulating the activity of cell surface receptors are provided. Receptor activity modulation occurs when exogenous bioactive compounds are contacted with the receptor activation domain. The modulation can be an increase in receptor activity or a decrease in ligand-induced receptor activity. Also provided are methods for identifying and screening for bioactive compounds.