COMPOSITIONS AND METHODS FOR TARGETING ANTIGEN-PRESENTING CELLS WITH ANTIBODY SINGLE-CHAIN VARIABLE REGION FRAGMENTS

摘要

Provided are single-chain Fv (scFv) fragment-based compositions and methods for targeting antigens to antigen-presenting cells (APCs) such as, for example, dendritic cells (DC). Compositions and methods disclosed herein are useful in the treatment of diseases including infectious diseases and cancer.