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Photocleavable agents and conjugates for the detection and isolation of biomolecules

机译:用于生物分子检测和分离的光裂解剂和结合物

摘要

The present invention relates to a bioreactive agent comprising a detectable moiety linked to a photo-reactive moiety, wherein said photoreactive moiety comprises at least one group covalently bound to a substrate to form a conjugate that can be selectively photocleaved to release said substrate, wherein said substrate is selected from proteins, peptides, amino acids, lipids, cells, virus particles, fatty acids, nucleic acids, nucleotides, nucleosides, oligonucleotides, polysaccharides and inorganic molecules.
机译:本发明涉及一种生物反应剂,其包含与光反应性部分连接的可检测部分,其中所述光反应性部分包含至少一个与底物共价结合以形成缀合物的基团,所述缀合物可以被选择性地光裂解以释放所述底物,其中底物选自蛋白质,肽,氨基酸,脂质,细胞,病毒颗粒,脂肪酸,核酸,核苷酸,核苷,寡核苷酸,多糖和无机分子。

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