INHIBITOR FOR SYNAPTIC PLASTICITY

摘要

PURPOSE: Provided is a synaptic plasticity inhibitor which has 35 glutamine repeat units. It is useful for the study of pathological mechanism of neurodegenerative diseases, such as Huntington's disease. CONSTITUTION: A synaptic plasticity inhibitor is characterized by containing huntington(htt) protein which is capable of inhibiting synaptic plasticity by forming aggregates and having 35 or more glutamine repeat units at N-terminal of the huntington protein.