Estradiol-TTS having water-binding additives

摘要

The present invention relates to a transdermal therapeutic system having a layered structure of a backing layer containing the active ingredient estradiol and being impermeable to the active substance and moisture, an active ingredient containing matrix and, if necessary, a removable protective layer covering the matrix, Characterized in that the matrix comprises glycerol which contains a maximum of 1% by weight of water or which is substantially free of water.