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A long-term storage method of blood and blood components.

机译:血液和血液成分的长期储存方法。

摘要

A method for inhibiting bacterial growth in whole blood and/or blood components, which may therefore also be used to extend the storage time for the whole blood and/or blood components, through treatment with carbon monoxide. This method is preferably used for the preservation of platelets, which are both particularly vulnerable to bacterial and other microbial infection, and which are also particularly suitable for use with the method of the present invention. Carbon monoxide may be present in an amount of from about 40% to about 100%. Platelets may be stored in a solution buffered by any suitable buffer, such as sodium bicarbonate. Platelet viability may be determined by measuring the ability to aggregate, for example in response to an agonist such as collagen.
机译:一种抑制全血和/或血液成分中细菌生长的方法,因此也可以用于通过用一氧化碳处理来延长全血和/或血液成分中的储存时间。该方法优选用于血小板的保存,所述血小板既特别易受细菌和其他微生物感染,又特别适合与本发明的方法一起使用。一氧化碳可以以约40%至约100%的量存在。血小板可以储存在由任何合适的缓冲液例如碳酸氢钠缓冲的溶液中。血小板活力可以通过测量聚集能力来确定,例如响应于诸如胶原的激动剂。

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