Electroporation device which reduces muscle contraction and pain sensation

摘要

An electroporation device comprising pulses generating circuit (3) connectable (5) to electrodes (7,8) fit table to a substrate (25) of a live being comprising cells; the electrodes (7,8) producing, in the substrate (25), an electric field which induces permeabilization of the membranes of the cells to facilitate introduction of substances (30) into the cells. A frequency regulating circuit (12) is designed to produce a train of pulses that are spaced one with respect the other of a, time interval Tsp that is lower than the refractory period of the nerves and/or muscles present in the substrate (25).