2-, 3-, 4- OR 5-SUBSTITUTED N-(1-(ARYL-, HETEROARYL- OR ARYLALKYL)SULFONYL) INDOLES AND THEIR USE IN THERAPY

摘要

The invention provides 2, 3-, 4- or 5-substituted-N-(1-(aryl-, heteroaryl- or arylalkyl) sulfonyl) indoles compounds of the general formula (I) in which Ar, R2, R3, R4 and R5 are as defined in the specification. The said compounds have affinity for the 5-HT6 receptor and are useful for the treatment and prophylaxis of disorders relating to the said receptor, such as obesity and CNS disorders.