首页> 外国专利> PROCESS FOR MANUFACTURING SUSTAINED RELEASED MICROBEADS CONTAINING VENLAFAXINE HCI THAT THE PROVISIONAL SPECIFICATION RELATING TO THIS INVENTION IS FILED WITH THIS APPLICATION

PROCESS FOR MANUFACTURING SUSTAINED RELEASED MICROBEADS CONTAINING VENLAFAXINE HCI THAT THE PROVISIONAL SPECIFICATION RELATING TO THIS INVENTION IS FILED WITH THIS APPLICATION

机译:制造含有文拉法辛HCl的缓释微珠的方法,本申请提供了与本发明有关的临时规范

摘要

The present invention relates to viable continuous process for manufacture of agglomeration free, high yield (generally atleast about 95% w/w), uniformly shaped and sized, stable novel pharmaceutical composition of adequate strength comprising upto about 70%w/w of Venlafaxine or its pharmaceutical acceptable salt which is free of organic acid for once a day dosing. Sustained release composition comprising of Venlafaxine HCI provides pH independent release of Venlafaxine HCI atleast for a period of 10 hours without any latent period and can be encapsulated in smallest capsule size 5 for therapeutic effective of Venlafaxine thus providing patient easy to consume dosage form. To
机译:本发明涉及制造无结块,高收率(通常至少约95%w / w),形状和大小均匀,尺寸稳定,具有足够强度的稳定的新型药物组合物的可行的连续方法,所述药物组合物包含约70%w / w的文拉法辛或每天一次,不含有机酸的可药用盐。包含文拉法辛HCl的缓释组合物可在10小时内无pH依赖性地释放文拉法辛HCl,无任何潜伏期,并且可以将其封装在5号最小胶囊中,以实现文拉法辛的治疗有效,从而为患者提供易于消费的剂型。至

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