Variants of allergic protein pratense phl p1 of phleum.

摘要

A hypoallergenic variant of the major allergen Phl p 1, wherein at least one of the lysine residues present at positions 28, 35, 44, 48, 179, 181, 183 and 185 of the mature protein Phl p 1 (SEQ . ID NO. 2 in which the residues at positions 28, 35, 44, 48, 179, 181, 183 and 185 are lysine) is replaced or removed.