PROCESS FOR PRODUCING ANTICANCER AGENT LL-D45042

摘要

The disclosure describes the production of anticancer agent LL-D45042, having the structure (I) by fermentation, to methods for the recovery and concentration of this anticancer agent from crude solutions, and to processes for the purification of this anticancer agent as well as a new microorganism of the species Streptomyces hygroscopicus LL-D45042 and mutants thereof useful in the preparation of this compound.