METHODS OF DIAGNOSING RENAL SALT WASTING SYNDROME AND ALZHEIMER'S DISEASE AND METHODS OF TREATING THE SAME

摘要

A method is described to diagnose (1) renal salt wasting syndrome and (2) Alzheimer's disease among dementia patients by measuring a patient's level of prostaglandin D2 synthase. Methods are also described to (1) treat renal salt wasting syndrome, (2) inhibit the rate of apoptosis or (3) prevent the onset of, or slow the rate of, progression of Alzheimer's disease. These methods involve inhibiting the rate of -Δ12prostaglandin J¿2? synthesis or by inhibiting the activity of -Δ?12¿prostaglandin J¿2?.