STABILISED PHARMACEUTICAL COMPOSITIONS AND PROCESS FOR THEIR PREPARATION COMPRISING AN ANTIBIOTIC AND AN EXPECTORANT

摘要

Compositions for the prophylactic or therapeutic treatment of bacterial diseases in humans and animals, comprising as essential active ingredients a quinolone- or naphtyridone-type antibiotic or an active chemical derivative thereof and bromhexine-HCl, glacial acetic acid, water and a stabilizing agent. The compositions are stable upon storage over a broad range of temperature. The invention concerns also the combined use of a quinolone- or naphtyridone-type antibiotic or an active chemical derivative thereof and bromhexine-HCl for the treatment of bacterial infections in humans and animals, and a process for the preparation of the aforementioned compositions.