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NADH-DEPENDENT CYTOCHROME B5 REDUCTASE AS A TARGET FOR HERBICIDES
NADH-DEPENDENT CYTOCHROME B5 REDUCTASE AS A TARGET FOR HERBICIDES
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机译:NADH依赖性细胞色素B5还原酶作为除草剂的目标
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摘要
The invention relates to the use of a polypeptide with the biological activity of an NADH-dependent cytochrome b5 reductase (E.C. 1.6.2.2), which when absent causes growth retardation and chlorotic foliage and is coded by the nucleic acid sequence SEQ ID NO:1 or functional equivalents of the aforementioned nucleic acid sequence, as a target for herbicides. Within this scope, functional equivalents of SEQ ID NO:1 are provided. The invention also relates to the use of the polypeptide with the biological activity of an NADH-dependent cytochrome b5 reductase in a method for identifying compounds with a herbicidal action, which inhibit NADH-dependent cytochrome b5 reductase. The invention further relates to the use of the compounds, which have been identified by the method, as herbicides.
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机译:本发明涉及具有NADH依赖性细胞色素b5还原酶(EC 1.6.2.2)的生物活性的多肽的用途,其不存在时会引起生长迟缓和褪绿叶,并由核酸序列SEQ ID NO:1编码。或上述核酸序列的功能等同物,作为除草剂的靶标。在此范围内,提供了SEQ ID NO:1的功能等同物。本发明还涉及具有NADH依赖性细胞色素b5还原酶的生物学活性的多肽在鉴定具有除草作用的化合物中的用途,所述化合物具有抑制NADH依赖性细胞色素b5还原酶的作用。本发明进一步涉及通过该方法鉴定的化合物作为除草剂的用途。
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