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Nadh-dependent cytochrome b5 reductase as target for herbicides
Nadh-dependent cytochrome b5 reductase as target for herbicides
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机译:Nadh依赖的细胞色素b5还原酶作为除草剂的靶标
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摘要
The present invention relates to the use of a polypeptide with the biological activity of an NADH-dependent cytochrome b5 reductase (E.C. 1.6.2.2), which, when not present, brings about growth retardation symptoms and chlorotic leaves, and which is encoded by the nucleic acid sequence SEQ ID NO:1 or functional equivalents of the abovementioned nucleic acid sequence, as target for herbicides. Functional equivalents of SEQ ID NO:1 are provided in this context. Moreover, the present invention relates to the use of the polypeptide with the biological activity of an NADH-dependent cytochrome b5 reductase in a method for identifying herbicidally active compounds which inhibit NADH-dependent cytochrome b5 reductase. Moreover, the invention relates to the compounds identified by the method for use as herbicides.
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机译:本发明涉及具有NADH依赖性细胞色素b5还原酶(EC 1.6.2.2)的生物活性的多肽的用途,当不存在该多肽时,会引起生长迟缓症状和褪绿叶,并由其编码。核酸序列SEQ ID NO:1或上述核酸序列的功能等同物,作为除草剂的靶标。在本文中提供了SEQ ID NO:1的功能等同物。此外,本发明涉及具有NADH依赖性细胞色素b5还原酶的生物学活性的多肽在鉴定抑制NADH依赖性细胞色素b5还原酶的除草活性化合物的方法中的用途。此外,本发明涉及通过该方法鉴定的用作除草剂的化合物。
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