that elicits an antibacterial effect and can be used in medicine. Invention provides preparing a new compound eliciting an antibacterial effect with respect to S. aureus, E. coli, and C. albicans with mononuclear cells values 0.25; 0.5 and 7.8 mcg/ml, respectively, and with acute toxicity value LD50 for these compounds 2 460 ± 230 mg/kg.;EFFECT: valuable properties of compound.;1 cl, 1 tbl, 2 ex"/>
6-NITRO-2-IMINOCOUMARIN 3-CARBOXYLIC ACID 4-TOLUIDIDE SILVER SALT ELICITING ANTIBACTERIAL ACTIVITY
6-NITRO-2-IMINOCOUMARIN 3-CARBOXYLIC ACID 4-TOLUIDIDE SILVER SALT ELICITING ANTIBACTERIAL ACTIVITY
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机译：6-硝基-2-亚氨基香豆素3-羧酸4-甲苯银盐抗菌活性
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摘要
FIELD: organic chemistry, medicine.;SUBSTANCE: invention relates to new compounds of coumarone class, namely, to 6-nitro-2-iminocoumarin 3-carboxylic acid 4-toluidide silver salt of the formula (1): that elicits an antibacterial effect and can be used in medicine. Invention provides preparing a new compound eliciting an antibacterial effect with respect to S. aureus, E. coli, and C. albicans with mononuclear cells values 0.25; 0.5 and 7.8 mcg/ml, respectively, and with acute toxicity value LD50 for these compounds 2 460 ± 230 mg/kg.;EFFECT: valuable properties of compound.;1 cl, 1 tbl, 2 ex
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机译：技术领域：本发明涉及香豆酮类新化合物，即式（1）的6-硝基-2-亚氨基香豆素3-羧酸4-甲苯酯银盐： 00000005.GIF“ he =” 25“ imgContent =” undefined“ imgFormat =” GIF“ wi =” 105“ />，具有抗菌作用，可用于医学领域。本发明提供了制备对单核细胞值为0.25;对金黄色葡萄球菌，大肠杆菌和白色念珠菌具有抗菌作用的新化合物。这些化合物的毒性分别为0.5和7.8 mcg / ml，急性毒性值为LD 50 2460±230 mg / kg .;作用：该化合物的有价值的特性; 1 cl，1 tbl，2前
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