Gene transfer crows gene expression method of gene transfer by avian retroviral vector and thereby obtained

摘要

Antibody gene is introduced by replication-defective retrovirus vector, an object of the invention is an antibody G0 transgenic chimera bird which is produced and G0 transgenic chimera bird producing an antibody by expressing the transgene expression to provide a method for the preparation of a G0 transgenic chimera bird, which consists in the antibody production method which consists in recovering the, and the furan fertilized avian eggs, and injection of retroviral vectors into fertilized later except the start of incubation after is. That is, the present invention is a G0 transgenic chimera bird of the antibody gene is introduced by replication-defective retrovirus vector to produce the antibody by expressing the transgene.