首页> 外国专利> Process for preparing 5-(4-fluorophenyl)-1-2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl) ethyl-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide

Process for preparing 5-(4-fluorophenyl)-1-2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl) ethyl-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide

机译:5-(4-氟苯基)-1- [2-(((2R,4R)-4-羟基-6-氧代-四氢-吡喃-2-基)乙基]乙基] -2-异丙基-4-苯基-的制备方法1H-吡咯-3-羧酸苯酰胺

摘要

A method for preparing 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide (I), a key intermediate in the synthesis of atorvastatin calcium, is described. embedded image
机译:一种5-(4-氟苯基)-1- [2-(((2R,4R)-4-羟基-6-氧代-四氢吡喃-2-基)-乙基] -2-异丙基-4-的制备方法描述了阿托伐他汀钙合成中的关键中间体苯基-1H-吡咯-3-羧酸苯基酰胺(I)。 <图像alt =“嵌入式图像” file =“ US20060106228A1-20060518-C00001.GIF” he =“ 54.36mm” imgContent =“ chem” imgFormat =“ GIF” wi =“ 69.93mm“ />

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