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Diagnostics and therapeutics for diseases associated with a new human 5-ht6 receptor

机译:新的人类5-ht6受体相关疾病的诊断和治疗

摘要

The present invention is directed to novel uses of a polynucleotide sequence of a novel G-Protein Coupled Receptor 5HT6. The invention also provides the human 5-HT6 receptor as being associated with hematological disorders, pain diseases, respiratory diseases, genito-urological disorders, cardio vascular diseases and cancer. The invention also provides assays for the identification of compounds useful for the modulation of hematological disorders, pain diseases, respiratory diseases, genito-uro-logical disorders, cardio vascular diseases and cancer for treating or preventing hematological disorders, pain diseases, respiratory diseases, genito-urological disorders, cardio vascular diseases and cancer associated with expression of the 5-HT6 receptor.
机译:本发明涉及新型G蛋白偶联受体5HT6的多核苷酸序列的新型用途。本发明还提供了与血液疾病,疼痛疾病,呼吸系统疾病,生殖泌尿疾病,心血管疾病和癌症有关的人5-HT6受体。本发明还提供用于鉴定化合物的测定法,所述化合物可用于调节血液疾病,疼痛疾病,呼吸系统疾病,生殖器泌尿系统疾病,心血管疾病和癌症,以治疗或预防血液疾病,疼痛疾病,呼吸系统疾病,生殖器疾病-HT疾病,心血管疾病和与5-HT6受体表达相关的癌症。

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