首页>
外国专利>
Inhibitor of the shh signalling patway and a testosterone supressing agent for the treatment of cancer
Inhibitor of the shh signalling patway and a testosterone supressing agent for the treatment of cancer
展开▼
机译:shh信号通路的抑制剂和睾丸激素抑制剂,用于治疗癌症
展开▼
页面导航
摘要
著录项
相似文献
摘要
A method of protecting a patient from possible adverse effects of a treatment involving inhibition of the SHH-signalling pathway in the patient, the method comprising suppressing testosterone or its effect in the patient. A method of treating a proliferative disease such as cancer in a patient the method comprising inhibiting the SHH-signalling pathway and suppressing testosterone or its effect in the patient. Typically, the SHH-signalling pathway is inhibited using cyclopamine or a derivative thereof, and testosterone is suppressed using any one or more of a GnRH antagonist, a GnRH agonist, an androgen antagonist or a Sa-reductase inhibitor.
展开▼