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Dioxocyclohexane carboxylic acid phenyl amide derivatives for modulating voltage-gated potassium channels and pharmaceutical compositions containing the same
Dioxocyclohexane carboxylic acid phenyl amide derivatives for modulating voltage-gated potassium channels and pharmaceutical compositions containing the same
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机译:用于调节电压门控钾通道的二氧环己烷羧酸苯基酰胺衍生物和含有该衍生物的药物组合物
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摘要
Dioxocyclohexane carboxylic acid phenyl amide derivatives of Formula (I) or a tautomer or a pharmaceutically acceptable salt thereof or both, and pharmaceutical compositions containing the same are provided: The dioxocyclohexane carboxylic acid phenyl amide derivatives are useful for treating a variety of conditions associated with the abnormal modulation of one or more Kv1.1 voltage-gated potassium channels.
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机译:提供了式(I)的二氧环己烷羧酸苯基酰胺衍生物或其互变异构体或其药学上可接受的盐或两者,以及包含它们的药物组合物: <图像alt =“嵌入式图像” file =“ US20060014826A1-20060119-C00001.GIF” he =“ 23.96mm” id =“ EMI-C00001” imgContent =“ chem” imgFormat =“ GIF” wi =“ 60.79mm” /> Chemistry>二氧环己烷羧酸苯基酰胺衍生物可用于治疗与一种或多种Kv1.1电压门控钾通道的异常调节有关的多种疾病。
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