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PHARMACEUTICAL FORMULATIONS

机译:药物配方

摘要

The invention relates to an inhalable solid pharmaceutical formulation comprising (a) an anti-cholinergic agent, (b) a carrier and (c) a ternary agent that is a sugar ester, an inhaler comprising such a formulation, a method of reducing or inhibiting chemical interaction between an active ingredient substance and a carrier susceptible to chemical interaction, a method of reducing or inhibiting chemical degradation of an active ingredient substance in a formulation comprising a carrier and an active ingredient substance, a method for the treatment of a reversible airways obstruction by administering to a patient in need thereof the inhalable solid pharmaceutical formulation, and a method of preparing a solid pharmaceutical preparation comprising combining (a) an anti-cholinergic agent, (b) a carrier and (c) a ternary agent that is a sugar ester.
机译:本发明涉及包含(a)抗胆碱能药,(b)载体和(c)作为糖酯的三元剂的可吸入固体药物制剂,包含该制剂的吸入器,减少或抑制方法活性成分物质与易发生化学相互作用的载体之间的化学相互作用,减少或抑制包含载体和活性成分物质的制剂中活性成分物质的化学降解的方法,治疗可逆性气道阻塞的方法通过向有需要的患者给药可吸入的固体药物制剂,以及制备固体药物制剂的方法,该方法包括将(a)抗胆碱能药,(b)载体和(c)作为糖的三元剂组合酯。

著录项

  • 公开/公告号WO2006076222A2

    专利类型

  • 公开/公告日2006-07-20

    原文格式PDF

  • 申请/专利权人 GLAXO GROUP LIMITED;TAYLOR MICHAEL K;

    申请/专利号WO2006US00447

  • 发明设计人 TAYLOR MICHAEL K;

    申请日2006-01-06

  • 分类号A61K9/12;A61K9/14;A61K31/16;A61K31/715;

  • 国家 WO

  • 入库时间 2022-08-21 21:30:08

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