A high purity polysaccharide containing hydrophobic group is produced by a process, comprising a first process step of producing an isocyanate group-containing hydrophobic compound, wherein one mole of a hydroxyl group-containing hydrocarbon having 12 - 50 carbon atoms or of a sterol is reacted with a diisocyanate represented by OCN-R1-NCO in which R1 is a hydrocarbyl of 1 - 50 carbon atoms, a second process step of producing the polysaccharide containing hydrophobic group composed of the hydrocarbon group of 12 - 50 carbon atoms or of the steryl group, wherein the isocyanate group-containing hydrophobic compound obtained in the first process step is reacted with one or more polysaccharides, and a purification step in which the reaction product in the second process step is purified using a solvent based on ketone.
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