polynukleotidsequenzen from corynebacterium glutamicum, succinatdehydrogenase subunits (sdha, sdhb, sdhc) encode

摘要

Isolated polynucleotide (I) from coryneform bacteria encoding succinate dehydrogenase, is new. Isolated polynucleotide (I) from coryneform bacteria encoding succinate dehydrogenase, is new. (I) is selected from: (a) a polynucleotide which is at least 70% identical with a sequence that encodes a polypeptide having the 293 (S3), 625 (S5) or 284 (S7) amino acids (aa) sequence defined in the specification; (b) a polynucleotide that encodes a polypeptide at least 70% identical with (S3), (S5) or (S7); (c) a polynucleotide that is complementary to (a)-(b); or (d) a polynucleotide that contains at least 15 consecutive nucleotides from (a)-(c). Independent claims are also included for the following: (1) vector containing (I); (2) coryneform bacteria containing the vector of (1); and (3) method for fermentative production of L-amino acids (A) by growing an (A)-producing coryneform bacterium in which at least one of the genes for succinate dehydrogenase or its A, B and C subunits is suppressed.