首页> 外国专利> METHOD, SYSTEM AND COMPOSITION FOR DIAGNOSIS, TREATMENT AND/OR PREVENTION OF CANCER, AND/OR FOR INHIBITING INVASION OR METASTASIS OF CANCER, AS WELL AS RELATED SCREENING METHOD

METHOD, SYSTEM AND COMPOSITION FOR DIAGNOSIS, TREATMENT AND/OR PREVENTION OF CANCER, AND/OR FOR INHIBITING INVASION OR METASTASIS OF CANCER, AS WELL AS RELATED SCREENING METHOD

机译:诊断,治疗和/或预防癌症和/或防止癌症的侵袭或转移的方法,系统和组合物以及相关的筛查方法

摘要

PPROBLEM TO BE SOLVED: To provide utterly novel techniques for diagnosis, treatment and/or prevention of cancers (especially small cell lung cancer) and/or for inhibition of invasion or metastasis of cancers. PSOLUTION: The invention provides a method of controlling invasion or metastasis of cancers, which is a method including (A) a step of controlling a molecular pathway of TSLC1 (tumor-suppressor gene in human non-small-cell lung cancer). The invention further provides a method of screening a regulator for metastasis and/or invasion of cancers, the method comprising (A) a step of providing candidate substances; (B) a step of providing the candidate substances to an assay system for the molecular pathway of TSLC1; and (C) a step of identifying a regulator for the molecular pathway of TSLC1 among the candidate substances, and determining the regulator as a regulator for invasion and/or metastasis of cancers. PCOPYRIGHT: (C)2007,JPO&INPIT
机译:

要解决的问题:提供用于诊断,治疗和/或预防癌症(尤其是小细胞肺癌)和/或抑制癌症的侵袭或转移的全新技术。解决方案:本发明提供了控制癌症的侵袭或转移的方法,该方法包括(A)控制TSLC1(人非小细胞肺癌中的肿瘤抑制基因)的分子途径的步骤。 。本发明进一步提供了一种筛选用于癌症转移和/或侵袭的调节剂的方法,该方法包括:(A)提供候选物质的步骤; (B)将候选物质提供给TSLC1分子途径的测定系统的步骤; (C)在候选物质中确定TSLC1的分子途径的调节剂,并将该调节剂确定为癌症的侵袭和/或转移的调节剂的步骤。

版权:(C)2007,日本特许厅&INPIT

著录项

  • 公开/公告号JP2007186492A

    专利类型

  • 公开/公告日2007-07-26

    原文格式PDF

  • 申请/专利权人 JAPAN HEALTH SCIENCE FOUNDATION;

    申请/专利号JP20060248743

  • 发明设计人 MURAKAMI YOSHINORI;MASUDA MARI;

    申请日2006-09-13

  • 分类号A61K45;A61K48;A61K38;A61K39/395;A61P35;A61K31/713;C12Q1/68;A01K67/027;C12N5/10;C12N15/09;G01N33/574;G01N33/50;G01N33/15;

  • 国家 JP

  • 入库时间 2022-08-21 21:15:01

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