Metabolic pathways altered bacterial strains with an increased accumulation of 2-keto-gluconic acid -D-

摘要

Had catalyzes the conversion of 2,5-Jiketogurukon acid to (2,5-DKG) 2- -D- keto gluconic acid from (2-KDG), the present invention, endogenous membrane-bound 2 before inactivation - By inactivating the (2-KDGDH) keto -D- gluconate dehydrogenase relates to a method of modifying the bacterial host cells to accumulate 2-KDG. [Selection Figure Figure 2