Neovascular inhibitor, DNA synthesis inhibitor, p44 / p42 MAPK phosphorylation inhibitor and medical kit

摘要

[PROBLEMS] To provide an anti-angiogenic agent comprising a novel peptide effective for the treatment of a disease associated with angiogenesis or a pharmacologically acceptable salt thereof, and the like [MEANS FOR SOLVING PROBLEMS] An anti-angiogenic agent comprising: an antibody directed against a peptide comprising an amino acid sequence lying between an amino acid residue at position-186 and an amino acid residue at position-385 in the amino acid sequence depicted in SEQ ID NO:1; and either one or both of a peptide comprising the amino acid sequence depicted in SEQ ID NO:2 or a pharmacologically acceptable salt thereof and a peptide comprising the amino acid sequence depicted in SEQ ID NO:3 or a pharmacologically acceptable salt thereof; and others.