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Phenylethenyl or phenylethynyl derivatives functioning as glutamate receptor antagonists

机译：苯基乙烯基或苯基乙炔基衍生物起谷氨酸受体拮抗剂的作用

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摘要

This invention relates to a compound and the use of the compound of the formula wherein RSUP1/SUP, RSUP2/SUP, RSUP3/SUP, RSUP4 /SUPand RSUP5 /SUPare as defined in the description, A signifies -CH-CH- or -C≡C-; and B signifies wherein RSUP6 /SUPto RSUP26/SUP, X and Y are as defined in the specification or a pharmaceutically acceptable salt thereof, for use in pharmaceutical compositions for the treatment or prevention of mGluR5 receptor mediated disorders.

机译：本发明涉及具有下式的化合物及其用途：其中R ^{1 ，R ^{2 ，R ^{3 ，R ^{4 和R ^{5 如描述中所定义，A表示-CH-CH-或-C≡C-; B表示其中R ^{6 至R ^{26 ，X和Y如说明书中所定义或其药学上可接受的盐，用于治疗或预防的药物组合物中mGluR5受体介导的疾病。}}}}}}}

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公开/公告号NO324326B1

专利类型
公开/公告日2007-09-24

原文格式PDF
申请/专利权人 F HOFFMANN-LA ROCHE AG;
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申请/专利号NO20030002503
发明设计人 WICHMANN JUERGEN;MUTEL VINCENT;PETERS JENS-UWE;
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申请日2003-06-03
分类号C07D233/64;C07D233/90;A61K31/4045;A61K31/415;A61K31/4164;A61K31/4174;A61K31/4178;A61K31/4245;A61K31/437;A61K31/4985;A61P1/08;A61P9/02;A61P9/10;A61P13/02;A61P21/02;A61P25;A61P25/04;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/34;A61P25/36;A61P31/18;A61P43;C07D209/14;C07D209/16;C07D231/12;C07D233/54;C07D233/58;C07D233/68;C07D233/92;C07D233/94;C07D403/06;C07D403/10;C07D413/04;C07D491/147;C07D495/14;C07D498/04;C07D513/14;
国家 NO
入库时间 2022-08-21 20:56:50

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