PROCESSES FOR PREPARING C-7 SUBSTITUTED 5-ANDROSTENES

摘要

This invention relates to processes for the preparation of novel , substituted steroid compounds of Formula 1, wherein R1 is H or. COR2; R2 is C1-C6 alkyl or Ct-C6 alkoxy; Z1 is CH2, or wherein OR3 is in the ¿ configuration; R3 is H or -COR2; Z2 is -CH-; or Z1 and Z2 may be taken together to form a carbon-carbon double bond; Q is or Y is --CN, -CH2-CH=CH2, C1-6. Alkyl C1-6 alkyl CHR4C (O)Ar, or CHR4 C (O)XC1-6 alkyl; CHR4(O)XAr, or CHR4 HC(O)XC1.6 alkyl; where R4 = O C1-6 alkyl or aryl X=Oor S i